For creative and innovative individuals who are looking to function as entrepreneurs in their own business or in creative roles within organizations, Grand Canyon University offers a Bachelor of Science in Entrepreneurial Studies program. Entrepreneurship is not just about starting a new business, but rather about recognizing opportunity and leading an organization to pursue it. The BS in Entrepreneurial Studies degree is built on the principles of personal integrity, values and innovation, and addresses key business areas including servant leadership, innovation and entrepreneurial spirit.

The BS in Entrepreneurial Studies degree explores the development of business plans, including the preparation of financial packages and the evaluation of opportunities, risks and problems associated with business development. Coursework also examines the importance of creating innovative work environments in small-, medium- and large-scale organizations in order to ensure the long-term competitiveness of the firm. Innovation is explored from the perspectives of product development, internal process improvement and strategic shifts. In addition, there is a focus on the growth of crowd funding and angel/venture capital market and the advantages and risks associated with each funding source.

Upon completing the BS in Entrepreneurial Studies degree, many graduates opt to further their education. GCU offers a variety of master's degrees in business including an MBA and a Master of Science in Leadership.